null

SMILES Cc1ncccc1-c1cnc(NCc2c3CCOc3ccc2F)n2cnc(C#N)c12

InChI Key InChIKey=ORRSIPZEJAGGKP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 450980   

LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 14.7nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 14.1nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450980(1-Ethynyl-N-((5-fluoro-2,3-dihydrobenzofuran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 48.9nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent