null

SMILES CS(=O)(=O)c1ncn2c(NCc3c4CCOc4ccc3F)ncc(-c3cccnc3C(F)F)c12

InChI Key InChIKey=XAYWQJNGHASKNL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 450981   

LigandPNGBDBM450981(8-(2-(Difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:To assess the compounds' potency in the EED-H3K27Me3 competition binding assay, compounds were serially diluted 3-fold in DMSO to obtain a total ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450981(8-(2-(Difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent
LigandPNGBDBM450981(8-(2-(Difluoromethyl)pyridin-3-yl)-N-((5-fluoro-2,...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Representative compounds of the present invention were serially and separately diluted 3-fold in DMSO to obtain a total of eight or twelve concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ64M9US Patent