null

SMILES Cc1cccnc1-c1cc(ccc1Cl)[C@@H](COC(=O)NC1CC1)N1C(=N)N[C@@](CC(C)(C)C)(C1=O)c1ccc(cc1F)-c1cnn(c1)C(F)F

InChI Key InChIKey=XIEMATKZJAJQEG-JQMWFGOGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 460898   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM460898(US10774053, Compound 12 | US11352329, COMPD # 12)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Compounds were tested in a high-throughput 384-well assay format for their ability to inhibit the replication of HIV-1 (IIIB) in MT-4 cells. Compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1NX9US Patent
TargetGag-Pol polyprotein(HIV-1)TBA
LigandPNGBDBM460898(US10774053, Compound 12 | US11352329, COMPD # 12)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibitor potency against HIV protease was measured using an enzymatic assay with a fluorogenic readout. To a reaction buffer containing 100 mM ammon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38WSQUS Patent
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM460898(US10774053, Compound 12 | US11352329, COMPD # 12)copy SMILEScopy InChI
Affinity DataEC50:  22.2nMAssay Description:Assay protocol is identical to that described for the MT-4 antiviral assay with the following changes: Each drug is run in 2 series of quadruplicates...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1NX9US Patent