null

SMILES Nc1nn(Cc2ccc(Cn3cc(F)ccc3=O)cc2)cc1C(=O)NCCOc1cccc(Cl)c1

InChI Key InChIKey=KZWKGQOVLZMLEU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 463423   

TargetPlasma kallikrein(Homo sapiens (Human))
KALVISTA PHARMACEUTICALS LIMITED

US Patent
LigandPNGBDBM463423(3-amino-N-[2-(3-chlorophenoxy)ethyl]-1-({4-[(5-flu...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods. Human plasma kallikrein (Protogen) was incubated at 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55RK5US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
KALVISTA PHARMACEUTICALS LIMITED

US Patent
LigandPNGBDBM463423(3-amino-N-[2-(3-chlorophenoxy)ethyl]-1-({4-[(5-flu...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetKallikrein-1(Homo sapiens (Human))
KALVISTA PHARMACEUTICALS LIMITED

US Patent
LigandPNGBDBM463423(3-amino-N-[2-(3-chlorophenoxy)ethyl]-1-({4-[(5-flu...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods. Human KLK1 (Callbiochem) was incubated at 25° C. with the fluoroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55RK5US Patent