null

SMILES C[C@](O)(Cn1ccc(n1)C(F)(F)F)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=UFQDJYUUEVLDSX-AWEZNQCLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 468333   

TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataKi:  512nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89PKUS Patent
TargetAndrogen receptor(Rattus norvegicus (Rat))TBA
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataKi:  512nMAssay Description:Displacement of [3H]-MIB from wild-type rat AR LBD measured after 16 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PHBPubMed
TargetAndrogen receptor [633-919](Homo sapiens (Human))TBA
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataKi:  512nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571GZ9
TargetAndrogen receptor [633-919](Homo sapiens (Human))TBA
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataKi:  512nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0QVNUS Patent
TargetAndrogen receptor [633-919](Homo sapiens (Human))TBA
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 205nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571GZ9
TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Antagonist activity at recombinant human AR expressed in HEK293 cells assessed as inhibition of R1881-induced transcriptional activity measured after...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PHBPubMed
TargetAndrogen receptor(Homo sapiens (Human))
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468333(US10806720, Compound 1014 | US11230523, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89PKUS Patent