null

SMILES C[C@](O)(Cn1cc(nn1)-c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=OEJFTOLGXGYZNB-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 468358   

TargetAndrogen receptor(Rattus norvegicus (Rat))TBA
LigandPNGBDBM468358(US10806720, Compound 1045 | US11648234, Compound 1...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H] MIB binding to rat prostate androgen receptor LBD by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6PTRPubMed
TargetAndrogen receptor [633-919](Homo sapiens (Human))TBA
LigandPNGBDBM468358(US10806720, Compound 1045 | US11648234, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 251nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571GZ9
TargetAndrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM468358(US10806720, Compound 1045 | US11648234, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 383nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK-293 cells harboring GRE-LUC and CMV-renilla luciferase assessed as inhibition of tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HH6PTRPubMed
TargetAndrogen receptor(Homo sapiens (Human))TBA
LigandPNGBDBM468358(US10806720, Compound 1045 | US11648234, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X89PKUS Patent