null

SMILES CN(C1CCN(C)CC1)C(=O)Nc1ccc2n(CC(=O)N(CC(=O)NCc3cccc(Cl)c3F)C3CC3)nc(C(N)=O)c2c1

InChI Key InChIKey=HOERATAUJMEIFL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 474862   

TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CW8PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 37nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5CW8PubMed
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6FZZUS Patent
TargetComplement factor D(Homo sapiens (Human))TBA
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used (Kam, C. M.; McRae, B. J.; Har...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN48Z8US Patent