null
SMILES Nc1ncnc2n(nc(Sc3cn[nH]c3)c12)[C@@H]1O[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]1O
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 475978
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme ATG7(Homo sapiens (Human))
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
MILLENNIUM PHARMACEUTICALS, INC.
US Patent
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair