null
SMILES Cc1ccccc1-n1ncc2C(CCCc12)NC(=O)c1noc2CCCCc12
InChI Key InChIKey=HUVJSRAMULDASL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 477599
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.
US Patent
Genase Therapeutics B.V.
US Patent
Affinity DataIC50: 5nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.
US Patent
Genase Therapeutics B.V.
US Patent
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate in presence of 2 nM of DHODH by DCIP assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.
US Patent
Genase Therapeutics B.V.
US Patent
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assayMore data for this Ligand-Target Pair