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SMILES Cc1cccc(c1C)-n1ncc2C(CCCc12)NC(=O)c1noc2CCCCc12

InChI Key InChIKey=KWESJWBFVAWPJT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477601   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.

US Patent
LigandPNGBDBM477601(N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N019MPUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.

US Patent
LigandPNGBDBM477601(N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate in presence of 2 nM of DHODH by DCIP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43F3PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics B.V.

US Patent
LigandPNGBDBM477601(N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43F3PubMed