null

SMILES Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCc1cccc(F)c1F

InChI Key InChIKey=GRHMMJHPAWJJGH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 48056   

TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM48056(3-amino-N-(2,3-difluorobenzyl)-4,6-dimethyl-thieno...)copy SMILEScopy InChI
Affinity DataEC50:  0.000973nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2251GKRPCBioAssay
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM48056(3-amino-N-(2,3-difluorobenzyl)-4,6-dimethyl-thieno...)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO Flp-In cells assessed as stimulation of acetylcholine-induced ERK1/2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S8DPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM48056(3-amino-N-(2,3-difluorobenzyl)-4,6-dimethyl-thieno...)copy SMILEScopy InChI
Affinity DataEC50:  105nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO Flp-In cells assessed as stimulation of acetylcholine-induced ERK1/2 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2S8DPubMed