null

SMILES CN1C(Cc2ccccc2)C(O)=C(C(=O)Nc2cccc(Sc3ncc(nc3N)N3CCC(C)(N)CC3)c2Cl)C1=O

InChI Key InChIKey=JJTYMCPMKUFMGA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484468   

TargetSH2B adapter protein 2(Human)
NOVARTIS AG

US Patent
LigandPNGBDBM484468(US10934285, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6H10US Patent