null

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(Nc2cccc(n2)N2CCNC2=O)nc1C

InChI Key InChIKey=DMIIPYYADLDKAX-HNNXBMFYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 489232   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489232(2-[(1S)-1-Cyclopropylethyl]-5-(4-methyl-2-{[6-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489232(2-[(1S)-1-Cyclopropylethyl]-5-(4-methyl-2-{[6-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 219nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489232(2-[(1S)-1-Cyclopropylethyl]-5-(4-methyl-2-{[6-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
LigandPNGBDBM489232(2-[(1S)-1-Cyclopropylethyl]-5-(4-methyl-2-{[6-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent