null

SMILES C[C@H](N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1sc(Nc2cccc(n2)N2CCCC2=O)nc1C)C(F)(F)F

InChI Key InChIKey=LLUGOCWVLNJQNI-AWEZNQCLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 489237   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489237(5-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489237(5-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 575nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM489237(5-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent
LigandPNGBDBM489237(5-(4-Methyl-2-{[6-(2-oxopyrrolidin-1-yl)pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CS5US Patent