null

SMILES CNc1nc(cs1)-c1ccc2N(CCc2c1)C(=O)c1ccccc1F

InChI Key InChIKey=DAKHCIUKYFQQEU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 49829   

TargetTranscription factor p65(Homo sapiens (Human))
SRMLSC

Curated by PubChem BioAssay
LigandPNGBDBM49829((2-fluorophenyl)(5-(2-(methylamino)thiazol-4-yl)in...)copy SMILEScopy InChI
Affinity DataEC50:  2.66E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8WT7PCBioAssay
TargetSerine/threonine-protein kinase WNK1 [198-401](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.

LigandPNGBDBM49829((2-fluorophenyl)(5-(2-(methylamino)thiazol-4-yl)in...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:For hit validation, eight compound replicates were made from the original stock dilution plates. The Cybi-WellTM dispenser was used to prepare 1.5 &#...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB51SQPubMed
TargetSerine/threonine-protein kinase WNK1 [198-401](Homo sapiens (Human))
Novartis Institutes for BioMedical Research, Inc.

LigandPNGBDBM49829((2-fluorophenyl)(5-(2-(methylamino)thiazol-4-yl)in...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:For hit validation, eight compound replicates were made from the original stock dilution plates. The Cybi-WellTM dispenser was used to prepare 1.5 &#...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB51SQPubMed
TargetNeuropilin-1(Homo sapiens (Human))
Burnham Center for Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM49829((2-fluorophenyl)(5-(2-(methylamino)thiazol-4-yl)in...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM5725PCBioAssay