null

SMILES CN(C1CCCCC1)C(=O)CCCOc1ccc2N=C3NC(=O)CN3Cc2c1

InChI Key InChIKey=WUECXCBONAGRSA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50000871   

TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataEC50:  440nMAssay Description:Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513X52PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24ZNBPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27946X0PubMed
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against platelet phosphodiesterase (PDE)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49T05PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysisMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513X52PubMed
TargetP2Y purinoceptor 12(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2513X52PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000871(CHEMBL69139 | N-Cyclohexyl-N-methyl-4-(2-oxo-1,2,3...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of platelet cAMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0JQQPubMed