null

SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12

InChI Key InChIKey=QPOLRENOYJQNEP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50001778   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TCG Lifesciences Ltd.

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 6.92nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ052WPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]-spiperone from Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CNKPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89BB3PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor of whole rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CNKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TCG Lifesciences Ltd.

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3FX0PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.0820nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z89BB3PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CNKPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck A/S

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Binding affinity at dopamine D2 receptor by [3H]-Spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0SKKPubMed