null

SMILES CN1C(=O)C(=C(C1=O)c1ccc(cc1)S(N)(=O)=O)c1ccc(Cl)cc1

InChI Key InChIKey=WKSXNSMQLGMRAB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001936   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50001936(CHEMBL3233602)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed