null

SMILES OC(=O)c1ccc2OCc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1

InChI Key InChIKey=WBPHAIFIMCCUJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50002750   

TargetThromboxane A2 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002750(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity at TXA2/PGH2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RG1PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002750(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002750(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002750(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory effect of the compound against thromboxane A2 synthase binding to bovine plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002750(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Compound was tested for its inhibitory activity against TXA2 synthase obtained from bovine platelet microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed