null

SMILES CC(C)(C)c1cc(cc(c1O)C(C)(C)C)-c1nnc(S)s1

InChI Key InChIKey=MYNMGQGXYYHMEX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50003127   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154G6NPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154G6NPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154G6NPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154G6NPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:The compound was tested for the inhibition of Prostaglandin G/H synthase in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D4B
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:The compound was tested for the inhibition of 5-lipoxygenase in intactbasophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668D4B
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase measured by the reduction of leukotriene B4 (LTB4) in intact basophilic rat leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10PVPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory activity against 5-LipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61KWBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61KWBPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50003127(CHEMBL122193 | CHEMBL1626562 | CHEMBL16659 | choli...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61TFPubMed