null

SMILES COc1cn(nc(-c2ccnn2-c2ccccc2)c1=O)-c1ccccc1F

InChI Key InChIKey=JBXPBSYUHPMEHH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003995   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50003995(CHEMBL2180009)copy SMILEScopy InChI

Affinity DataIC50: 12nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))TBA

LigandBDBM50003995(CHEMBL2180009)copy SMILEScopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of human full length PDE10A expressed in SF21 cells using [3H]cGMP as substrate after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XJKPubMed