null

SMILES CN1C2CCC1[C@@H](\C=C\Cl)[C@H](C2)c1ccc(Cl)cc1

InChI Key InChIKey=TUWFHUVJRFWFJU-FCLJUXRZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50004167   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.220nMAssay Description:Binding constant for the ability to displace [3H]mazindol to dopamine receptor was calculated from the Cheng-Prusoff relationshipMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.880nMAssay Description:Binding constant for [3H]dopamine uptake was calculated from the Cheng-Prusoff relationshipMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]mazindol from dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004167((2R,3S)-3-(4-Chloro-phenyl)-2-((E)-2-chloro-vinyl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.990nMAssay Description:Inhibitory concentration against [3H]dopamine uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4JZN