null

SMILES OC(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=HCUARRIEZVDMPT-UHFFFAOYSA-N

PDB links: 6 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50004955   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50P5KPubMed
TargetD-amino-acid oxidase(Sus scrofa (pig))
Sunovion Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Competitive inhibition of pig kidney DAAO in presence of D-alanineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92CPCPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of FITC-Bak-BH3 peptide from Mcl-1 (unknown origin) incubated for 1.5 hrs by FPA competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59HHPubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5P46PubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
California Institute of Technology

LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+6nMAssay Description:Kinetic assay using chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2214PubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
California Institute of Technology

LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+6nMAssay Description:Kinetic assay using chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2214PubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
California Institute of Technology

LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  4.50E+6nMAssay Description:Kinetic assay using chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2214PubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
California Institute of Technology

LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataKi:  5.70E+6nMAssay Description:Kinetic assay using chymotrypsin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N2214PubMed
TargetD-aspartate oxidase(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03KSPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Merck Sharp & Dohme

Curated by ChEMBL
LigandPNGBDBM50004955(1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...)copy SMILEScopy InChI
Affinity DataIC50: 745nMAssay Description:Inhibition of human DAOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03KSPubMed