null

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C

InChI Key InChIKey=SIIICDNNMDMWCI-LMRVLLHPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50005576   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  0.380nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90992PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90992PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Affinity against cocaine binding site of dopamine transporter in rat striatum using [3H]2b as radioligand.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2X4ZPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Potency for the inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6K0FPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60PQ2PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60PQ2PubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60PQ2PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Concentration required to inhibit 50% of radioligand binding ([3H]WIN-35428) to the dopamine (DA) transporter in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1XH0PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]WIN-35428 binding at dopamine transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]nisoxetine binding at norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T3JPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Compounds binding ability to dopamine transporter was evaluated by displacing [3H]-beta-CFT in baboon brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7TQDPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix Inc.

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Compounds binding ability to serotonin transporter was evaluated by displacing [3H]-paroxetine in baboon brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HD7TQDPubMed