null

SMILES O=C(CNC(=O)c1ccnc2ncnn12)N1CCC[C@H]1C#N

InChI Key InChIKey=JYTXLAIYDQBXKG-VIFPVBQESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50009357   

TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DFWPubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP2 purified from human seminal plasma using Lys-Ala-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DFWPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DFWPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center

US Patent
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP4 purified from human seminal plasma using Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84DFWPubMed
TargetProlyl endopeptidase(Homo sapiens (Human))
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50009357(CHEMBL3233575 | US9346814, Cmpd No 30 Example 35)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V6DUS Patent