null

SMILES CC(C)c1ccc(NC(N)=Nc2ccc(cc2)C(C)C)cc1

InChI Key InChIKey=WIULPOAMZNPPJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010754   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)copy SMILEScopy InChI
Affinity DataIC50: 242nMAssay Description:Tested in vitro for the concentration required to inhibit specific [3H]-DTG radioligand binding to sigma receptor on guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1BRZPubMed
TargetSodium channel protein type 2 subunit alpha(Rattus norvegicus)
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52Q8WPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Cambridge NeuroScience, Inc.

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:In vitro inhibitory activity against [3H]DTG binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4WQ3PubMed