null

SMILES CN(C)CC(c1cccc(c1)C(F)(F)F)C1(O)CCCCC1

InChI Key InChIKey=YUTGLCAFRPAGFA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50010884   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 534nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WCMPubMed
TargetTransporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of norepinephrine uptake at rat brain norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WCMPubMed
TargetTransporter(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WCMPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50010884(1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of 5HT uptake at rat brain SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16PBPubMed