null

SMILES CN1CC[C@@H]([C@H](O)[C@H](CC2CCCCC2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)C1=O

InChI Key InChIKey=GMHADIRIDUBUJL-ZIUUJSQJSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50011703   

TargetPepsin A(Porcine)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against PepsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed
TargetGastricsin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against GastricsinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed
TargetRenin(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMpH: 7.4Assay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed
TargetCathepsin E(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against cathepsin EMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed
TargetCathepsin D(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50011703(CHEMBL355128 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against cathepsin DMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6DGKPubMed