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SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC

InChI Key InChIKey=CANPFCFJURGKAX-JTQLQIEISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50012961   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.261nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280860PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.430nMAssay Description:Inhibition constant against dopamine receptor D2 in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4Q10PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  0.633nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C24X1VPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]spiperone from dopamine D2short receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3JVDPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]spiperone from dopamine D3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3JVDPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]spiperone from dopamine D2long receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3JVDPubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of [3H]SCH23990 from dopamine D1 receptor in pig stratial membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3JVDPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In vivo inhibitory activity of the compound against dopamine (D2) receptor in rat caudate-putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M07BCPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:In vitro binding affinity at Dopamine receptor D2 in rat by displacing [3H]- spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ2BHDPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataKd:  0.430nMAssay Description:Evaluated in vivo for the affinity towards Dopamine receptor D2 of rat striatal tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2280860PubMed
TargetD(1A) dopamine receptor(RAT)
Yale University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:In vivo binding affinity of the compound against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M07BCPubMed
TargetD(1A) dopamine receptor(RAT)
Yale University

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo binding affinity of the compound against dopamine (D2) receptor in rat caudate-putamen tissue using [3H]-nemonapride as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M07BCPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50012961((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:In vivo inhibitory activity of the compound against dopamine (D1) receptor in rat caudate-putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M07BCPubMed