null

SMILES O=C1N(CCn2ncc3cccc1c23)[C@@H]1CN2CCC1CC2

InChI Key InChIKey=MBYAMJFNDALRJQ-OAHLLOKOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50014550   

Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataKi:  8nM ΔG°:  -11.0kcal/molepH: 7.5 T: 2°CAssay Description:The relative affinity of the various compounds for the human 5-HT3 receptor was measured in a radioligand binding assay, using a scintillation proxim...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6BN0US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataKi:  8.10nMAssay Description:Displacement of [9-methyl-3H]BRL-43694 from human 5-HT3A receptor after overnight incubation by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataEC50:  178nMAssay Description:Agonist activity at mouse 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Albany Molecular Research, Inc.

US Patent
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5-HT3A receptor expressed in HEK293 cells in presence of carbacholMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
AMRI

Curated by ChEMBL
LigandPNGBDBM50014550(CHEMBL3261481 | US9045501, 7)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ09VXPubMed