null

SMILES CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=KRPOBUBNNHJTKL-OVFSYLBISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50014732   

TargetNeutrophil elastase(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Binding affinity against human Elastase for more active diasteriomerMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5RZ5PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Compound was evaluated In vitro for inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81SJ
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Binding affinity against human Cathepsin GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5RZ5PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity against human ElastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5RZ5PubMed
TargetCathepsin G(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi: >6.00E+5nMAssay Description:Binding affinity against human Cathepsin GMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5RZ5PubMed
TargetChymotrypsin-like elastase family member 1(Homo sapiens (Human))
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50014732(1-{2-[2-(5-Dimethylamino-naphthalene-1-sulfonylami...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+6nMAssay Description:Binding affinity against human ElastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5RZ5PubMed