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SMILES CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC

InChI Key InChIKey=ZQBULZYTDGUSSK-KRWDZBQOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50015677   

TargetProtein kinase C delta type(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  6.80nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NQ6PubMed
TargetProtein kinase C eta type(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of [3H]- PDBu binding to peptide D of mouse skin Protein kinase C etaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4QMM
TargetProtein kinase C alpha type(Bos taurus (bovine))
National Cancer Institute at Frederick

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H995WHPubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:Displacement of [20-3H] phorbol 12,13-dibutyrate from protein kinase C alphaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G16011PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  40nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5GJ1PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  2.82E+3nM ΔG°:  -7.39kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NQ6PubMed
TargetProtein kinase C gamma type(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  2.93E+3nMAssay Description:Inhibition of [3H]- PDBu binding to peptide C, rat brain PKC gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4QMM
TargetProtein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  6.70E+3nM ΔG°:  -6.89kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NQ6PubMed
TargetSerine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataKi:  6.96E+3nM ΔG°:  -6.87kcal/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NQ6PubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataEC50:  5.24E+3nMAssay Description:Binding affinity to GST-tagged PKCtheta expressed in Escherichia coli BL21(DE3) by fluorescence quenchingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP834VPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataEC50:  1.62E+4nMAssay Description:Binding affinity to GST-tagged PKCdelta expressed in Escherichia coli BL21(DE3) by fluorescence quenchingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP834VPubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
University of Houston

Curated by ChEMBL
LigandPNGBDBM50015677((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester | 1,...)copy SMILEScopy InChI
Affinity DataEC50:  8.19E+3nMAssay Description:Binding affinity to GST-tagged PKCepsilon expressed in Escherichia coli BL21(DE3) by fluorescence quenchingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP834VPubMed