null

SMILES CC1CC(=O)NN=C1c1ccc(cc1)-n1cnc2CCCCc12

InChI Key InChIKey=KDEKNYKHIZTSLE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50016839   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibitory concentration against cGMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibitory concentration against cAMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibitory concentration against cGMP PDE I enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of dual cGMP-inhibited phosphodiesterase 3 (PDE3) was determined in homogenates from human platelets.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S1857BPubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against cAMP PDE III enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 MMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27083P1PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50016839(5-Methyl-6-[4-(4,5,6,7-tetrahydro-benzoimidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibitory concentration against cAMP PDE II enzyme in guinea pigMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27S7MS4PubMed