null
SMILES [H][C@@]12CC[C@@](C)(c3c1c(=O)n(-c1ccccn1)n3C)C2(C)C
InChI Key InChIKey=QYTUGODFCXAKLV-DIFFPNOSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50018812
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat 11betaHSD1 assessed as reduction of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.
Curated by ChEMBL
Hoffmann-La Roche Inc.
Curated by ChEMBL
Affinity DataIC50: 634nMAssay Description:Inhibition of full-length human 11betaHSD1 expressed in HEK293 cells assessed as cortisol level by competitive ELISAMore data for this Ligand-Target Pair