null

SMILES CCCN(CCC)C1CCc2c(O)cccc2C1

InChI Key InChIKey=MDBWEQVKJDMEMK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50020221   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  0.660nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C9SPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Tested in vitro for the inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P56
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WJ9PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28QZPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023VMPubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G8CPubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]spiperone from rat D3 dopamine receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CNFPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Tested in vitro for the inhibition of [3H]-U-86,170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P56
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-N-0437 from human Dopamine receptor D2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C9SPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067NPPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3C9SPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  58.8nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G8CPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  58.8nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023VMPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  58.8nMAssay Description:Displacement of [3H]spiperone from rat D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WJ9PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  153nMAssay Description:Displacement of [3H]spiperone from rat D2L dopamine receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85CNFPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  344nMAssay Description:Tested in vitro for the inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor, expressed in cloned CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P56
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£ di Catania

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  466nMAssay Description:Binding affinity to 5-HT7 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BPMPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Medicinaregatan

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataKi:  1.04E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X067NPPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataEC50:  0.140nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G8CPubMed
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:50% inhibition of specific [3H]clonidine binding (0.4 nM) to Alpha-2 adrenergic receptors in rat isolated brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24B31WHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
State University of Groningen

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Potency to displace the specific in vitro binding of [3H]-N-0437 to calf striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3S82PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataEC50:  10.4nMAssay Description:Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7G8CPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Potency to displace the specific in vitro binding of [3H]DP-5,6-ADTN to rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22R3S82PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataEC50:  41.2nMAssay Description:Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023VMPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataEC50:  1.23nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023VMPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.4 nM) to rat isolated brain membr...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24B31WHPubMed