null

SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1n[nH]c2CC3(CC3)CCc12

InChI Key InChIKey=STCNDRXGYAQSKS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50022976   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022976(CHEMBL3298291)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022976(CHEMBL3298291)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Inhibition of human His-tagged full length AURKA using kemptide peptide as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022976(CHEMBL3298291)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of ITK in human Jurkat cells assessed as reduction in PLC-gamma phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed