null

SMILES Nc1nc2CCC(CN(CC#C)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)Cc2c(=O)[nH]1

InChI Key InChIKey=ZOLYPGWZGDQXCC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50024473   

TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in permeabilised L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+6nMAssay Description:Evaluated for the inhibition of thymidylate synthase in intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Evaluated for the inhibition of dihydrofolate reductase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50024473(2-{4-[(2-Amino-4-oxo-3,4,5,6,7,8-hexahydro-quinazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PRCPubMed