null
SMILES COc1ccc(C(=O)Nc2cccc(c2)C(O)=O)c(NC(=O)c2ccc(cc2)C(C)(C)C)c1
InChI Key InChIKey=NGPVBEGYGDKDJE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50028447
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Activity at TGR5 in human NCI-H716 cells assessed as effect on intracellular cAMP accumulation incubated for 60 mins by HTR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Activity at GAL4-tagged PPARdelta (unknown origin) expressed in COS7 cells assessed as receptor transactivation by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at human FXR expressed in human HeLa cells assessed as receptor activation by BSEP promoter-driven firefly luciferase reporter gene ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at GAL4-tagged PPARalpha (unknown origin) expressed in COS7 cells assessed as receptor transactivation by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 2.99E+3nMAssay Description:Activity at GAL4-tagged PPARgamma (unknown origin) expressed in COS7 cells assessed as receptor transactivation by luciferase reporter gene assayMore data for this Ligand-Target Pair