null

SMILES CCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C

InChI Key InChIKey=PLKVKLNGSGPVQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50030694   

TargetType-2 angiotensin II receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81C35PubMed
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81C35PubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81C35PubMed
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1W0S
TargetType-2 angiotensin II receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.930nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81C35PubMed
TargetType-1 angiotensin II receptor(RABBIT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1W0S
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030694(CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:In vitro inhibitory activity against Angiotensin II receptor type 2 in human adrenal membrane preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q81C35PubMed