null
SMILES Nc1nc(N)c2c(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)coc2n1
InChI Key InChIKey=ACXZKUHGYNILFP-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50030820
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration of the compound against Lactobacillus casei TS (Thymidylate synthase).More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration of the compound against recombinant human DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:inhibitory concentration of the compound against Lactobacillus casei DHFR(Dihydro folate reductase).More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against recombinant human (rh) Thymidylate synthase (TS)More data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against human TSMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against human dihydrofolate reductase (DHFR),More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair