null

SMILES CCC[C@@H]1C2CCC(C[C@@H]1c1ccccc1)N2C

InChI Key InChIKey=ZWPCJQABQGIZIQ-VUROTCPHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50032537   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]dopamine binding to rat striatal synaptosome dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Binding affinity towards dopamine transporter using [3H]-mazindol as radioligand in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KS6S69PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Binding affinity for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Binding affinity of compound on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataKi:  87nMAssay Description:Binding affinity for Serotonin transporter was determined by [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibitory activity against Serotonin transporter was determined for [3H]5-HT (serotonin) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity on dopamine transporters of rat striated membranes using [3H]- mazindol.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Mayo Foundation for Medical Education and Research

Curated by ChEMBL
LigandPNGBDBM50032537((2S,3S)-8-Methyl-3-phenyl-2-propyl-8-aza-bicyclo[3...)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity determined for [3H]DA (Dopamine transporter) uptake by striated synaptosomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1RQ7PubMed