null

SMILES [O-][N+](=O)c1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=KBEUKMLEXDGSBY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033324   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Biofor Inc.

Curated by ChEMBL
LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F190CBPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49T8RPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells preincubated for 30 mins prior to Hoechst 33342 addition measured every 60 secs up to 120 mins by H...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7JD9PubMed