null

SMILES [H][C@]12OCCC[C@]1(C)Oc1ccc(cc1[C@@]21CSC(N)=N1)-c1cc(F)cc(Cl)c1

InChI Key InChIKey=YYSIZDVURBDWGB-JBACZVJFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033409   

TargetBeta-secretase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50033409(CHEMBL3357668)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of purified recombinant human BACE1 expressed in CHO cells assessed as uncleaved biotinylated sAPP after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348N0TPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50033409(CHEMBL3357668)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing swedish double mutant APP assessed as amyloid beta (1 to 40) peptide level after 7 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348N0TPubMed
TargetCathepsin B(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50033409(CHEMBL3357668)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of cathepsin D purified from human spleen after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348N0TPubMed