null

SMILES COc1cc(CNc2ccc3nc(N)nc(N)c3c2Cl)cc(OC)c1OC

InChI Key InChIKey=VYLYXKMAGOPZRD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50035481   

TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035481(5-Chloro-N*6*-(3,4,5-trimethoxy-benzyl)-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of Dihydrofolate reductase of Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Institute

Curated by ChEMBL
LigandPNGBDBM50035481(5-Chloro-N*6*-(3,4,5-trimethoxy-benzyl)-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Dihydrofolate reductase (DHFR) of in rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50035481(5-Chloro-N*6*-(3,4,5-trimethoxy-benzyl)-quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6RVDPubMed