null

SMILES CC(C)OC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2C

InChI Key InChIKey=ZAQLTGAFVMGUMB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50035725   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]DA uptake by rat striatal dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Ratio of Ki value towards Serotonin transporter to that of dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Binding affinity at the Serotonin transporter in rat midbrain by inhibition of 0.5 nM [3H]-paroxetine bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50035725(3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...)copy SMILEScopy InChI
Affinity DataIC50: 285nMAssay Description:Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine bindingMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D50NM0PubMed