null

SMILES COc1ccc(OC)c(c1)N(C)Cc1cccc2nc(N)nc(N)c12

InChI Key InChIKey=NVHYXHSWQXQWAQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50036492   

TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50036492(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-q...)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Inhibitory activity against Leu22-Phe mutant human Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11PKPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50036492(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-q...)copy SMILEScopy InChI
Affinity DataKi: >500nMAssay Description:Inhibitory compound against Wild-type human DHFR.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11PKPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50036492(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-q...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11PKPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50036492(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-q...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory activity against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11PKPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50036492(5-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-q...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibitory activity against rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ11PKPubMed