null

SMILES COc1ccc(CNc2nc(OCc3ccccn3)ncc2C(=O)OCc2ncccn2)cc1Cl

InChI Key InChIKey=IMXBLVJBNGJENV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036611   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA

LigandBDBM50036611(CHEMBL3354265)copy SMILEScopy InChI

Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X35250PubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL

LigandBDBM50036611(CHEMBL3354265)copy SMILEScopy InChI

Affinity DataIC50: 4.20nMAssay Description:Inhibition of dog lungs PDE5 using [3H]cGMP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9S1WPubMed