null
SMILES C[C@]12CCC3C(CN=C4CC(=O)CC[C@]34C)C1CC[C@@H]2C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1
InChI Key InChIKey=HGVJAJYYFXHPED-XXRHFDIKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50039259
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity for human 5 alpha reductase 1 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
Target3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1(Homo sapiens (Human))
Pfizer Central Research
Curated by ChEMBL
Pfizer Central Research
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Binding affinity for 3-beta-hydroxysteroid dehydrogenaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Glaxo Inc. Research Institute
Curated by ChEMBL
Glaxo Inc. Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Glaxo Inc. Research Institute
Curated by ChEMBL
Glaxo Inc. Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Binding affinity for human 5-alpha reductase 2 isozymeMore data for this Ligand-Target Pair
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Glaxo Inc. Research Institute
Curated by ChEMBL
Glaxo Inc. Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair