null

SMILES C[C@]12CCC3C(CN=C4CC(=O)CC[C@]34C)C1CC[C@@H]2C(=O)N1CCSCC1

InChI Key InChIKey=QLGRLIPMYCDDEH-PAJIOFOTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039284   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039284((1S,9aR,11aS)-9a,11a-Dimethyl-1-(thiomorpholine-4-...)copy SMILEScopy InChI
Affinity DataKi:  570nMAssay Description:Inhibition of recombinant human 5-alpha reductase-1 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F76PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039284((1S,9aR,11aS)-9a,11a-Dimethyl-1-(thiomorpholine-4-...)copy SMILEScopy InChI
Affinity DataKi:  570nMAssay Description:In vitro inhibitory activity against human type 1 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q228088WPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039284((1S,9aR,11aS)-9a,11a-Dimethyl-1-(thiomorpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibitory activity against human type 2 5-alpha reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q228088WPubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50039284((1S,9aR,11aS)-9a,11a-Dimethyl-1-(thiomorpholine-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of recombinant human 5-alpha reductase-2 at a concentration of 5 microL after preincubation for 10 minutesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F76PubMed