null

SMILES Cc1c(CNc2ccc(Cl)c(Cl)c2)cnc2nc(N)nc(N)c12

InChI Key InChIKey=DCPBQWMARMWVCT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50042351   

TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibitory concentration against Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8KR5PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8KR5PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8KR5PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8KR5PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833R62PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TQ3PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833R62PubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antimycobacterial activity against human dihydrofolate reductase (hDHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9VXRPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Lindsley F. Kimball Research Institute

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Antimycobacterial activity against Mycobacterium avium complex diihydrofolate reductase (MAC DHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9VXRPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TQ3PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40TQ3PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042351(6-[(3,4-Dichloro-phenylamino)-methyl]-5-methyl-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2833R62PubMed